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On-going Research Project

• How the cortical and striatal microcircuit involves in reward-based decision making 
   (by Dr. Hyun-Jung Lee)
• How the cortical and striatal microcircuit involves in social interaction behaviours
   (by Dr. Mootaek Roh)
• Role of Epac2 in social interaction behaviours and stress-induced depression-like 

   behaviours (by Hyunhyo Seo & Jihye Kwak)

• Role of Epac2 in the regulation of autophagy activity and adult neurogenesis 

  (by Jihye Kwak and collaboration with Prof. Jin-A Lee from Hannam Univ.)


Research Technical Tools

• Mouse Genetics

 - cre-loxp mouse line

• Mouse Behavioural Analysis

 - Open field / Elevated Plus Maze / T-maze

 - Forced swimming / tail suspension task

 - Home cage activity recording

 - Two armed bandit task

 - 3-chamber task 

 - 3-CSRTT

• In Vivo Electrophysiology using tetrode microdrive

 - Multi-unit recording

 - EEG recording

• Optogenetics for electrophysiological recording & behavioural analysis

 - Channelrhodopsin

 - Halorhodopsin

• Cellular, Molecular, and Biochemical study

 - Primary neuron culture, Neural stem cell culture

 - Neuroblastoma cell culture (with neural differentiation)

 - Protein analysis (Western blot)

 - Immunohistochemistry / Immunocytochemistry

 - FACS / ELISA

• Human-derived cell culture

 - skin fibroblast culture

 - urine-derived renal cell culture


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