Publications

Publications

  • Dong Il Choi, Myeongwon Kim, Somi Kim, Nam‑Kyung Yu, Chuljung Kwak, Hyunhyo Seo, Kyungmin Lee* and Bong‑Kiun Kaang. Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency. Mol Brain (2021) 14:1  https://doi.org/10.1186/s13041-020-00716-z.
  • Juhyun Lee and Kyungmin Lee. Parvalbumin-expressing GABAergic interneurons and perineuronal nets in the prelimbic and orbitofrontal cortices in association with basal anxiety-like behaviors in adult mice. Behavioural Brain Research. 2020 Sep. 10. accepted.
  • Ji-Hye Kwak, Somi Kim, Nam-Kyung Yu, Hyunhyo Seo, Ja Eun Choi, Ji-il Kim, Dong Il Choi, Myung Won Kim, Chuljung Kwak, Bong-Kiun Kaang, and Kyungmin Lee. Loss of the neuronal genome organizer and transcription factor CTCF induces neuronal death and reactive gliosis in the anterior cingulate cortex. Genes, Brain and Behavior. 2021 Feb. 8.  
  • Mootaek Roh, Hyunjung Lee, Hyunhyo Seo, Chae-Seok Lim, Pojeong Park, Ja Eun Choi, Ji-Hye Kwak, Juhyun Lee, Bong-Kiun Kaang, Thomas J. McHugh, and Kyungmin Lee. Perseverative stereotypic behavior of Epac2 KO mice in a reward-based decision making task. NeuroScience Research. 2020 Dec. 21.
  • Nam Gyu Hyun, Kwang-Ho Hyun, Saecheol Oh, and Kyungmin Lee. Analysis of Temperature-dependent Abnormal Bursting Patterns of Aplysia’s Neurons. Korean J Physiol Pharmacol. 2020;24(4):349-362. doi.org/10.4196/kjpp.2020.24.4.349
  • You-Kyung Lee, Su-Kyeong Hwang, Soo-Kyung Lee, Jung-eun Yang, Ji-Hye Kwak, Hyunhyo Seo, Hyunjun Ahn, Yong-Seok Lee, Janghwan Kim, Chae-Seok Lim, Bong-Kiun Kaang, Jae-Hyung Lee, Jin-A Lee and Kyungmin Lee. Cohen syndrome patient iPSC-derived neurospheres and forebrain-like glutamatergic neurons reveal reduced proliferation of neural progenitor cells and altered expression of synapse genes. J. Clin. Med. 2020, 9(6), 1886. doi:10.3390/jcm9061886
  • You-Kyung Lee, Soo-Kyeong Lee, Suin Choi, Yang Hoon Huh, Ji-Hye Kwak, Yong-Seok Lee, Deok-Jin Jang, Jae-Hyung Lee, Kyungmin Lee, Bong-Kiun Kaang, Chae-Seok Lim and Jin-A Lee. Autophagy pathway upregulation in a human iPSC-derived neuronal model of Cohen syndrome with VPS13B missense mutations. Mol Brain. 2020; 13:69. doi:10.1186/s13041-020-00611-7
  • Yong-Seok Lee, Nam-Kyung Yu, Jeewan Chun, Jung-eun Yang, Chae-Seok Lim, Hyopil Kim, Gaeun Park, Jin-A Lee, Kyungmin Lee, Bong-Kiun Kaang and Jae-Hyung Lee. Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder. Mol Brain. 2020; 13:54. doi:10.1186/s13041-020-00595-4
  • Min Jung Kim, Ro Un Lee, Jihae Oh, Ja Eun Choi, Hyopil Kim, Kyungmin Lee, Su-Kyeong Hwang, Jae-Hyung Lee, Jin-A Lee, Bong-Kiun Kaang, Chae-Seok Lim and Yong-Seok Lee. Spatial Learning and Motor Deficits in Vacuolar Protein Sorting-associated Protein 13b (Vps13b) Mutant Mouse. Exp Neurobiol. 2019 Aug;28(4):485-494. doi:10.5607/en.2019.28.4.485
  • Hyunhyo Seo and Kyungmin Lee. Cell-specific expression of Epac2 in the subventricular and subgranular zones. Mol. Brain 2019; 12:113. doi:10.1186/s13041-019-0537-1
  • Somi Kim, Nam-Kyung Yu, Kyu-Won Shim, Ji-il Kim, Hyopil Kim, Dae Hee Han, Ja Eun Choi, Seung-Woo Lee, Dong Il Choi, Myung Won Kim, Dong-Sung Lee, Kyungmin Lee, Niels Galjart, Yong-Seok Lee, Jae-Hyung Lee, and Bong-Kiun Kaang. Remote Memory and Cortical Synaptic Plasticity Require Neuronal CCCTC-Binding Factor (CTCF). J. Neurosci. 2018 May; 38(22):5042–5052. doi:10.1523/JNEUROSCI.2738-17.2018
  • Hyoung-Gon Ko, Sanghyun Ye, Dae-Hee Han, Pojeong Park, Chae-Seok Lim, Kyungmin Lee, Min Zhuo, and Bong-Kiun Kaang. Transcription-independent expression of PKMζ in the anterior cingulate cortex contributes to chronically maintained neuropathic pain. Mol Pain. 2018; 14:1–8. doi: 10.1177/1744806918783943
  • Ji Yun Lee, Kyung Min Lee, Duk Hee Lee and Dong Sun Kim. Association of low-dose exposure to persistent organic pollutants with E-cadherin promoter methylation in healthy Koreans. Biomarkers. 2018 May;23(3):293-298. doi: 10.1080/1354750X.2017.1417482.
  • Sukjae Joshua Kang, Siyong Kim, Jaehyun Lee, Chuljung Kwak, Kyungmin Lee, Min Zhuo and Bong-Kiun Kaang. Inhibition of anterior cingulate cortex excitatory neuronal activity induces conditioned place preference in a mouse model of chronic inflammatory pain. Korean J Physiol Pharmacol. 2017; 21(5):487-493. doi:10.4196/kjpp.2017.21.5.487
  • Su-Kyeong Hwang, Jae-Hyung Lee, Jung-eun Yang, Chae-Seok Lim, Jin-A Lee, Yong-Seok Lee, Kyungmin Lee and Bong-Kiun Kaang. Everolimus improves neuropsychiatric symptoms in a patient with tuberous sclerosis carrying a novel TSC2 mutation. Mol Brain. 2016 May 23;9(1):56. doi: 10.1186/s13041-016-0222-6.
  • Hyunhyo Seo and Kyungmin Lee. Epac2 contributes to PACAP-induced astrocytic differentiation through calcium ion influx in neural precursor cells. BMB Rep. 2016 Feb;49(2):128-33.
  • Mootaek Roh, Kyungmin Lee, Il-Sung Jang, Kyoungho Suk, Maan-Gee Lee. Acrylic Resin Molding Based Head Fixation Technique in Rodents. J Vis Exp. 2016 Jan 12;(107). doi: 10.3791/53064.
  • Chae-Seok Lim, Jung-eun Yang, You-Kyung Lee, Kyungmin Lee, Jin-A Lee, Bong-Kiun Kaang. Understanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients. Mol Brain. 2015 Sep 30;8(1):57
  • Mootaek Roh, Thomas J. McHugh, and Kyungmin Lee. A video based feedback system for control of an active commutator during behavioral physiology. Mol Brain. 2015; 8: 61
  • Kyungmin Lee, Yuki Kobayashi, Hyunhyo Seo, Ji-Hye Kwak, Akira Masuda, Chae-Seok Lim, Hye-Ryeon Lee, SukJae Joshua Kang, Pojeong Park, Su-Eon Sim, Naomi Kogo, Hiroaki Kawasaki, Bong-Kiun Kaang, Shigeyoshi Itohara. Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility. Mol Brain. 2015 Jun 24;8:38
  • Kyungmin Lee. Neuroglial Cells : An Overview of Their Physiological Roles and Abnormalities in Mental Disorders. Korean J Biol Psychiatry 2015;22(2):29-33
  • Jihye Park, Chae-Seok Lim, Hyunhyo Seo, Chung-Ah Park, Min Zhuo, Bong-Kiun Kaang, and Kyungmin Lee. Pain perception in acute model mice of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Mol Pain. 2015 May 17;11:28
  • Hyunhyo Seo, Myoung-Jin Seol, and Kyungmin Lee. Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. Mol Brain. 2015 Feb 27;8:13
  • Nam Gyu Hyun, Kwang-Ho Hyun, Kwang-Beom Hyun, Kyungmin Lee. Temperature-dependent bursting pattern analysis by modified Plant model. Mol Brain. 2014 Jul 22;7:50
  • Su-Eon Sim, Hye-Ryeon Lee, Jae-Ick Kim, Sun-Lim Choi, Joseph Bakes, Deok-Jin Jang, Kyungmin Lee, Kihoon Han, Eunjoon Kim, Bong-Kiun Kaang. Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression. BMB Rep. 2013 Feb;46(2):103-6.
  • Jeehaeh Do, Jae-Ick Kim, Joseph Bakes, Kyungmin Lee, Bong-Kiun Kaang. Functional roles of neurotransmitters and neuromodulators in the dorsal striatum. Learning & Memory. 2012 Dec: 20(1):21-8
  • Ki-Jun Yoon, Hye-Ryeon Lee, Yong Sang Jo, Kyongman An, Sang-Yong Jung, Min-Woo Jeong, Seok-Kyu Kwon, Nam-Shik Kim, Hyun-Woo Jeong, Seo-Hee Ahn, Kyong-Tai Kim, Kyungmin Lee, Eunjoon Kim, Joung-Hun Kim, June-Seek Choi, Bong-Kiun Kaang, Young-Yun Kong. Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway. Mol. Brain. 2012 Oct: 5(1):40
  • Chuljung Kwak, Jun-Hyeok Choi, Joseph T. Bakes, Kyungmin Lee, and Bong-Kiun Kaang. Effect of Intensity of Unconditional Stimulus on Reconsolidation of Contextual Fear Memory. Korean J Physiol Pharmacol. 2012 Oct:16:293-296.
  • Yong-Seok Lee, Sun-Lim Choi, Heejung Jun, Se-Jeong Yim, Jin-A Lee, Hyoung F. Kim, Seung-Hee Lee, Jaehoon Shim, Kyungmin Lee, Deok-Jin Jang, and Bong-Kiun Kaang. AU-rich element-binding protein negatively regulates CCAAT enhancer-binding protein mRNA stability during long-term synaptic plasticity in Aplysia. PNAS. 2012 Aug:109(38):15520-15525.
  • Sue-Hyun Lee, Chuljung Kwak, Jaehoon Shim, Jung-Eun Kim, Sun-Lim Choi, Hyoung F. Kim, Deok-Jin Jang, Jin-A Lee, Kyungmin Lee, Chi-Hoon Lee, Young-Don Lee, Maria Concetta Miniaci, Craig H. Bailey, Eric R. Kandel, and Bong-Kiun Kaang. A cellular model of memory reconsolidation involves reactivation-induced destabilization and restabilization at the sensorimotor synapse in Aplysia. PNAS. 2012 Aug:109(35):14200-14205.
  • SukJae Joshua Kang, Ming-Gang Liu, Tao Chen, Hyoung-Gon Ko, Gi-Chul Baek, Hye-Ryeon Lee, Kyungmin Lee, Graham L. Collingridge, Bong-Kiun Kaang, and Min Zhuo. Plasticity of Metabotropic Glutamate Receptor-Dependent Long-Term Depression in the Anterior Cingulate Cortex after Amputation. J. Neurosci. 2012 Aug:32(33):11318-11329.
  • Hyejung Won, Hye-Ryeon Lee3, Heon Yung Gee4, Won Mah, Jae-Ick Kim, Jiseok Lee, Seungmin Ha, Changuk Chung, Eun Suk Jung, Yi Sul Cho, Sae-Geun Park, Jung-Soo Lee, Kyungmin Lee, Daesoo Kim, Yong Chul Bae, Bong-Kiun Kaang, Min Goo Lee & Eunjoon Kim. Autistic-like social behaviour in Shank2-mutant mice improved by restoringNMDAreceptor function. Nature. 2012 Jun:486:261-265.
  • Nam Gyu Hyun, Kwang-Ho Hyun, Kyungmin Lee, Bong-Kiun Kaang. Temperature Dependence of Action Potential Parameters in Aplysia Neurons. Neurosignals. 2012 Jan:20:252-264.
  • Céline S. Nicolas, Stéphane Peineau, Mascia Amici, Zsolt Csaba, Assia Fafouri, Charlotte Javalet, Valerie J. Collett, Lars Hildebrandt, Gillian Seaton, Sun-Lim Choi, Su-Eon Sim, Clarrisa Bradley, Kyungmin Lee, Min Zhuo, Bong-Kiun Kaang, Pierre Gressens, Pascal Dournaud, Stephen M. Fitzjohn, Zuner A. Bortolotto, Kwangwook Cho & Graham L. Collingridge. The JAK/STAT pathway is involved in synaptic plasticity. Neuron. 2012 Jan:73:374-390.
  • Su-Eon Sim, Soo-Won Park, Sun-Lim Choi, Nam-Kyung Yu, Hyoung-Gon Ko, Deok-Jin Jang, Kyungmin Lee & Bong-Kiun Kaang. Assessment of the effects of virus-mediated limited Oct4 overexpression on the structure of the hippocampus and behavior in mice. BMB reports. 2011 Dec:44(12):793-798.
  • Nam Gyu Hyun, Kwang-Ho Hyun, Kwang-Beom Hyun, Jin-Hee Han, Kyungmin Lee, and Bong-Kiun Kaang. A Computational Model of the Temperature-dependent Changes in Firing Patterns in Aplysia Neurons. Korean J Physiol Pharmacol. 2011 Dec:15:371-382.
  • Bolam Lee, Giannina Descalzi, Jinhee Baek, Jae-Ick Kim, Hye-Ryeon Lee, Kyungmin Lee, Bong-Kiun Kaang, and Min Zhuo. Genetic Enhancement of Behavioral Itch Responses in Mice Lacking Phosphoinositide 3-kinase-gamma (PI3Kgamma). Mol. Pain, 2011 Dec:7(96).
  • Kim JI, Lee HR, Sim SE, Baek JH, Yu NK, Choi JH, Ko HG, Park SW, Ahn SJ, Choi SY, Lee YS, Jang DJ, Kim KH, Lee KM, Bradley CA, Kim H, Kim EJ, Min Zhuo, Kim SJ, Peter H. Backx, Graham L. Collingridge and Kaang BK. PI3Kγ is required for NMDAR-dependent long-term depression and behavioral flexibility. Nat. Neurosci. 2011 Nov:14(11):1447-1454.
  • Li XY, Ko HG, Chen Tao, Descalzi Giannina, Koga Kohei, Wang Hansen, Kim SS, Shang Yuze, Kwak CJ, Park SW, Shim JH, Lee KM, Graham Collingridge, Kaang BK, Zhuo Min. Alleviating Neuropathic Pain Hypersensitivity by Inhibiting PKM zeta in the Anterior Cingulate Cortex. Science. 2010 Dec:330:1400-1404.
  • Lee KM, Cho HJ. Interleukin-6-induced upregulation of spinal fractalkine receptors via p38 MAPK signaling contributes to the pain facilitation in a rat model of nerve injury. Eur. J. Pain. 2010 Aug:14(7):794-806.
  • Lee KM, Jeon SM, Cho HJ. Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB but not p38 MAPK activation in the spinal cord and dorsal root ganglia in a rat neuropathic pain model. Eur. J. Pain. 2009 Sep:13(8): 794-806.
  • Lee KM, Jagn JH, Park JS, Kim DS, Han HS. Effect of Mild Hypothermia on Blood Brain Barrier Disruption Induced by Oleic Acid in Rats. Genes & Genomics. 2009 Feb:31(1):89-98
  • Jeon SM, Lee KM, Cho HJ. Expression of monocyte chemoattractant protein-1 in rat dorsal root ganglia and spinal cord in experimental models of neuropathic pain. Brain Research. 2009 Jan:1251:103-111.
  • Jeon SM, Lee KM, Park ES, Jeon YH, Cho HJ. MCP-1 immunoreactivity in sensory ganglia and hindpaw after adjuvant-injection. Neuroreport. 2008 Jan 22;19(2):183-186
  • Kim JK, Jeon SM, Lee KM, Park ES, Cho HJ. Expression of brain-derived neurotrophic factor in the rat forebrain and upper brain stem during postnatal development: an immunohistochemical study. Neuroscience. 2007 May 25;146(3):1128-1136.
  • Son SJ, Lee KM, Jeon SM, Park ES, Park KM, Cho HJ. Activation of transcription factor c-jun in dorsal root ganglia induces VIP and NPY upregulation and contributes to the pathogenesis of neuropathic pain. Exp Neurol. 2007 Mar;204(1):467-472.
  • Lee KM, Kang BS, Lee HL, Son SJ, Hwang SH, Kim DS, Park JS, Cho HJ. Spinal NF-kB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity. Eur J Neurosci. 2004 Jun;19(12):3375-3381.
  • Lee HL, Lee KM, Son SJ, Hwang SH, Cho HJ. Temporal expression of cytokines and their receptors mRNAs in a neuropathic pain model. Neuroreport. 2004 Dec 22;15(18):2807-2811.
  • Kim SY, Bae JC, Kim JY, Lee HL, Lee KM, Kim DS, Cho HJ. Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury. Neuroreport. 2002 Dec 20;13(18):2483-2486.